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In mitragynine the phenolic methyl ether is considered to be stronger in analgesic paradigms according to some studies. In southern Thailand kratom chewers generally start at around the age of 25 and many continue to chew the leaves for the rest of their lives. A fresh leaf Super Green Malay Kratom Mitragyna Speciosa Leaf weighs on average 2 grams. The average number of leaves consumed is between 10 and 60 Super Green Malay Kratom Mitragyna Speciosa Leaf leaves per day but even more than this is common. In some areas of southern Thailand upwards of 70% of the male population uses kratom on a daily basis. Kratom and its derivatives have been used as substitutes for opium as well as for the management of opium withdrawal. Data on the incidence and prevalence of its use are lacking as physicians are generally unfamiliar with it and its use is not detected by typical drug screening tests.